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Signaling properties of the human chemokine receptors CXCR4 and CXCR7 by cellular electric impedance measurements

The chemokine receptor 4 (CXCR4) and 7 (CXCR7) are G-protein-coupled receptors involved in various diseases including human cancer. As such, they have become important targets for therapeutic intervention. Cell-based receptor assays, able to detect agents that modulate receptor activity, are of key...

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Detalles Bibliográficos
Autores principales: Doijen, Jordi, Van Loy, Tom, De Haes, Wouter, Landuyt, Bart, Luyten, Walter, Schoofs, Liliane, Schols, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612718/
https://www.ncbi.nlm.nih.gov/pubmed/28945785
http://dx.doi.org/10.1371/journal.pone.0185354