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Exosomal lncRNA GAS5 regulates the apoptosis of macrophages and vascular endothelial cells in atherosclerosis

Atherosclerosis is universally recognized as a chronic lipid-induced inflammation of the vessel wall. Oxidized low density lipoprotein (oxLDL) drives the onset of atherogenesis involving macrophages and endothelial cells (ECs). Our earlier work showed that expression of long noncoding RNA-growth arr...

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Detalles Bibliográficos
Autores principales: Chen, Lei, Yang, Wenjin, Guo, Yijun, Chen, Wei, Zheng, Ping, Zeng, Jinsong, Tong, Wusong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612752/
https://www.ncbi.nlm.nih.gov/pubmed/28945793
http://dx.doi.org/10.1371/journal.pone.0185406