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Efficacy and Safety of Pancreas-Targeted Hydrodynamic Gene Delivery in Rats

Development of an effective, safe, and convenient method for gene delivery to the pancreas is a critical step toward gene therapy for pancreatic diseases. Therefore, we tested the possibility of applying the principle of hydrodynamic gene delivery for successful gene transfer to pancreas using rats...

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Detalles Bibliográficos
Autores principales: Ogawa, Kohei, Kamimura, Kenya, Kobayashi, Yuji, Abe, Hiroyuki, Yokoo, Takeshi, Sakai, Norihiro, Nagoya, Takuro, Sakamaki, Akira, Abe, Satoshi, Hayashi, Kazunao, Ikarashi, Satoshi, Kohisa, Junji, Tsuchida, Masanori, Aoyagi, Yutaka, Zhang, Guisheng, Liu, Dexi, Terai, Shuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612811/
https://www.ncbi.nlm.nih.gov/pubmed/29246326
http://dx.doi.org/10.1016/j.omtn.2017.08.009