ICM conversion to epiblast by FGF/ERK inhibition is limited in time and requires transcription and protein degradation

Inner cell Mass (ICM) specification into epiblast (Epi) and primitive endoderm (PrE) is an asynchronous and progressive process taking place between E3.0 to E3.75 under the control of the Fibroblast Growth Factor (FGF)/Extracellular signal-Regulated Kinase (ERK) signaling pathway. Here, we have anal...

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Detalles Bibliográficos
Autores principales: Bessonnard, Sylvain, Coqueran, Sabrina, Vandormael-Pournin, Sandrine, Dufour, Alexandre, Artus, Jérôme, Cohen-Tannoudji, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612930/
https://www.ncbi.nlm.nih.gov/pubmed/28947813
http://dx.doi.org/10.1038/s41598-017-12120-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612930/
https://www.ncbi.nlm.nih.gov/pubmed/28947813
http://dx.doi.org/10.1038/s41598-017-12120-0

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