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Stable MOB1 interaction with Hippo/MST is not essential for development and tissue growth control

The Hippo tumor suppressor pathway is essential for development and tissue growth control, encompassing a core cassette consisting of the Hippo (MST1/2), Warts (LATS1/2), and Tricornered (NDR1/2) kinases together with MOB1 as an important signaling adaptor. However, it remains unclear which regulato...

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Detalles Bibliográficos
Autores principales: Kulaberoglu, Yavuz, Lin, Kui, Holder, Maxine, Gai, Zhongchao, Gomez, Marta, Assefa Shifa, Belul, Mavis, Merdiye, Hoa, Lily, Sharif, Ahmad A. D., Lujan, Celia, Smith, Ewan St. John, Bjedov, Ivana, Tapon, Nicolas, Wu, Geng, Hergovich, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612953/
https://www.ncbi.nlm.nih.gov/pubmed/28947795
http://dx.doi.org/10.1038/s41467-017-00795-y