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Premature contractions of the bladder are suppressed by interactions between TRPV4 and SK3 channels in murine detrusor PDGFRα(+) cells

During filling, urinary bladder volume increases dramatically with little change in pressure. This is accomplished by suppressing contractions of the detrusor muscle that lines the bladder wall. Mechanisms responsible for regulating detrusor contraction during filling are poorly understood. Here we...

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Detalles Bibliográficos
Autores principales: Lee, Haeyeong, Koh, Byoung H., Peri, Lauren E., Corrigan, Robert D., Lee, Hyun-Tai, George, Nikita E., Bhetwal, Bhupal P., Xie, Yeming, Perrino, Brian A., Chai, Toby C., Sanders, Kenton M., Koh, Sang Don
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613012/
https://www.ncbi.nlm.nih.gov/pubmed/28947806
http://dx.doi.org/10.1038/s41598-017-12561-7