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Premature contractions of the bladder are suppressed by interactions between TRPV4 and SK3 channels in murine detrusor PDGFRα(+) cells
During filling, urinary bladder volume increases dramatically with little change in pressure. This is accomplished by suppressing contractions of the detrusor muscle that lines the bladder wall. Mechanisms responsible for regulating detrusor contraction during filling are poorly understood. Here we...
Autores principales: | Lee, Haeyeong, Koh, Byoung H., Peri, Lauren E., Corrigan, Robert D., Lee, Hyun-Tai, George, Nikita E., Bhetwal, Bhupal P., Xie, Yeming, Perrino, Brian A., Chai, Toby C., Sanders, Kenton M., Koh, Sang Don |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613012/ https://www.ncbi.nlm.nih.gov/pubmed/28947806 http://dx.doi.org/10.1038/s41598-017-12561-7 |
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