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Cohesin Can Remain Associated with Chromosomes during DNA Replication

To ensure disjunction to opposite poles during anaphase, sister chromatids must be held together following DNA replication. This is mediated by cohesin, which is thought to entrap sister DNAs inside a tripartite ring composed of its Smc and kleisin (Scc1) subunits. How such structures are created du...

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Detalles Bibliográficos
Autores principales: Rhodes, James D.P., Haarhuis, Judith H.I., Grimm, Jonathan B., Rowland, Benjamin D., Lavis, Luke D., Nasmyth, Kim A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613076/
https://www.ncbi.nlm.nih.gov/pubmed/28930671
http://dx.doi.org/10.1016/j.celrep.2017.08.092