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MYC Immunohistochemistry Predicts MYC Rearrangements by FISH

MYC is the proto-oncogene classically associated with Burkitt lymphoma (BL) located at chromosomal locus 8q24. Rearrangements of MYC are seen in nearly 100% of BL but have been reported in 3–16% of diffuse large B-cell lymphomas (DLBCLs). Rearrangements of MYC are tested for by flourescence in situ...

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Detalles Bibliográficos
Autores principales: Nwanze, Julum, Siddiqui, Momin T., Stevens, Keith A., Saxe, Debra, Cohen, Cynthia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613089/
https://www.ncbi.nlm.nih.gov/pubmed/28983465
http://dx.doi.org/10.3389/fonc.2017.00209