The Effects of SEA0400 on Ca(2+) Transient Amplitude and Proarrhythmia Depend on the Na(+)/Ca(2+) Exchanger Expression Level in Murine Models

Background/Objective: The cardiac Na(+)/Ca(2+) exchanger (NCX) has been identified as a promising target to counter arrhythmia in previous studies investigating the benefit of NCX inhibition. However, the consequences of NCX inhibition have not been investigated in the setting of altered NCX express...

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Detalles Bibliográficos
Autores principales: Bögeholz, Nils, Schulte, Jan S., Kaese, Sven, Bauer, B. Klemens, Pauls, Paul, Dechering, Dirk G., Frommeyer, Gerrit, Goldhaber, Joshua I., Kirchhefer, Uwe, Eckardt, Lars, Pott, Christian, Müller, Frank U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613119/
https://www.ncbi.nlm.nih.gov/pubmed/28983248
http://dx.doi.org/10.3389/fphar.2017.00649

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613119/
https://www.ncbi.nlm.nih.gov/pubmed/28983248
http://dx.doi.org/10.3389/fphar.2017.00649

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