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Helicobacter pylori CagA Protein Negatively Regulates Autophagy and Promotes Inflammatory Response via c-Met-PI3K/Akt-mTOR Signaling Pathway

Cytotoxin-associated-gene A (CagA) of Helicobacter pylori (H. pylori) is a virulence factor that plays critical roles in H. pylori-induced gastric inflammation. In the present study, gastric biopsies were used for genotyping cagA and vacA genes, determining the autophagic activity, and the severity...

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Detalles Bibliográficos
Autores principales: Li, Na, Tang, Bin, Jia, Yin-ping, Zhu, Pan, Zhuang, Yuan, Fang, Yao, Li, Qian, Wang, Kun, Zhang, Wei-jun, Guo, Gang, Wang, Tong-jian, Feng, You-jun, Qiao, Bin, Mao, Xu-hu, Zou, Quan-ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613121/
https://www.ncbi.nlm.nih.gov/pubmed/28983474
http://dx.doi.org/10.3389/fcimb.2017.00417