Cargando…

Human Tregs Made Antigen Specific by Gene Modification: The Power to Treat Autoimmunity and Antidrug Antibodies with Precision

Human regulatory CD4(+) T cells (Tregs) are potent immunosuppressive lymphocytes responsible for immune tolerance and homeostasis. Since the seminal reports identifying Tregs, vast research has been channeled into understanding their genesis, signature molecular markers, mechanisms of suppression, a...

Descripción completa

Detalles Bibliográficos
Autores principales: Adair, Patrick R., Kim, Yong Chan, Zhang, Ai-Hong, Yoon, Jeongheon, Scott, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613123/
https://www.ncbi.nlm.nih.gov/pubmed/28983300
http://dx.doi.org/10.3389/fimmu.2017.01117