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Generation and Characterization of α9 and α10 Nicotinic Acetylcholine Receptor Subunit Knockout Mice on a C57BL/6J Background

We generated constitutive knockout mouse models for the α9 and α10 nicotinic acetylcholine receptor (nAChR) subunits by derivation from conditional knockouts by breeding with CRE deleter mice. We then backcrossed them onto a C57BL/6J genetic background. In this manuscript, we report the generation o...

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Detalles Bibliográficos
Autores principales: Morley, Barbara J., Dolan, David F., Ohlemiller, Kevin K., Simmons, Dwayne D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613126/
https://www.ncbi.nlm.nih.gov/pubmed/28983232
http://dx.doi.org/10.3389/fnins.2017.00516