The EspF N-Terminal of Enterohemorrhagic Escherichia coli O157:H7 EDL933w Imparts Stronger Toxicity Effects on HT-29 Cells than the C-Terminal

Enterohemorrhagic Escherichia coli (EHEC) O157:H7 EspF is an important multifunctional protein that destroys the tight junctions of intestinal epithelial cells and promotes host cell apoptosis. However, its molecular mechanism remains elusive. We knocked out the espF sequence (747 bp, ΔespF), N-term...

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Detalles Bibliográficos
Autores principales: Wang, Xiangyu, Du, Yanli, Hua, Ying, Fu, Muqing, Niu, Cong, Zhang, Bao, Zhao, Wei, Zhang, Qiwei, Wan, Chengsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613159/
https://www.ncbi.nlm.nih.gov/pubmed/28983470
http://dx.doi.org/10.3389/fcimb.2017.00410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613159/
https://www.ncbi.nlm.nih.gov/pubmed/28983470
http://dx.doi.org/10.3389/fcimb.2017.00410

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