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Loss of Sphingosine Kinase Alters Life History Traits and Locomotor Function in Caenorhabditis elegans

Sphingolipid metabolism is important to balance the abundance of bioactive lipid molecules involved in cell signaling, neuronal function, and survival. Specifically, the sphingolipid sphingosine mediates cell death signaling, whereas its phosphorylated form, sphingosine-1-phosphate (S1P), mediates c...

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Detalles Bibliográficos
Autores principales: Chan, Jason P., Brown, Jaylene, Hark, Brandon, Nolan, Abby, Servello, Dustin, Hrobuchak, Hannah, Staab, Trisha A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613162/
https://www.ncbi.nlm.nih.gov/pubmed/28983319
http://dx.doi.org/10.3389/fgene.2017.00132