Population Pharmacokinetics/Pharmacodynamics of 3,4‐Diaminopyridine Free Base in Patients With Lambert‐Eaton Myasthenia

Lambert‐Eaton myasthenia (LEM) is a rare autoimmune disorder associated with debilitating muscle weakness. There are limited treatment options and 3,4‐diaminopyridine (3,4‐DAP) free base is an investigational orphan drug used to treat LEM‐related weakness. We performed a population pharmacokinetic/p...

Descripción completa

Detalles Bibliográficos
Autores principales: Thakkar, Nilay, Guptill, Jeffrey T., Aleš, Kathy, Jacobus, David, Jacobus, Laura, Peloquin, Charles, Cohen‐Wolkowiez, Michael, Gonzalez, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613184/
https://www.ncbi.nlm.nih.gov/pubmed/28623849
http://dx.doi.org/10.1002/psp4.12218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613184/
https://www.ncbi.nlm.nih.gov/pubmed/28623849
http://dx.doi.org/10.1002/psp4.12218

Ejemplares similares