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Population Pharmacokinetics/Pharmacodynamics of 3,4‐Diaminopyridine Free Base in Patients With Lambert‐Eaton Myasthenia

Lambert‐Eaton myasthenia (LEM) is a rare autoimmune disorder associated with debilitating muscle weakness. There are limited treatment options and 3,4‐diaminopyridine (3,4‐DAP) free base is an investigational orphan drug used to treat LEM‐related weakness. We performed a population pharmacokinetic/p...

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Detalles Bibliográficos
Autores principales:	Thakkar, Nilay, Guptill, Jeffrey T., Aleš, Kathy, Jacobus, David, Jacobus, Laura, Peloquin, Charles, Cohen‐Wolkowiez, Michael, Gonzalez, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613184/ https://www.ncbi.nlm.nih.gov/pubmed/28623849 http://dx.doi.org/10.1002/psp4.12218

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