Developing a Natural History Progression Model for Duchenne Muscular Dystrophy Using the Six‐Minute Walk Test

The 6‐minute walk test (6MWT) is used as a clinical endpoint to evaluate drug efficacy in Duchenne Muscular Dystrophy (DMD) trials. A model was developed using digitized 6MWT data that estimated two slopes and two intercepts to characterize 6MWT improvement during development and 6MWT decline. Mean...

Descripción completa

Detalles Bibliográficos
Autores principales: Hamuro, Lora, Chan, Phyllis, Tirucherai, Giridhar, AbuTarif, Malaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613187/
https://www.ncbi.nlm.nih.gov/pubmed/28643370
http://dx.doi.org/10.1002/psp4.12220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613187/
https://www.ncbi.nlm.nih.gov/pubmed/28643370
http://dx.doi.org/10.1002/psp4.12220

Ejemplares similares