RP S19 C-terminal peptide trimer acts as a C5a receptor antagonist

We have demonstrated that ribosomal protein S19 (RP S19) polymer, when crosslinked between Lys122 and Gln137 by activated coagulation factor XIII, acts as a C5a receptor (C5aR) antagonist/agonist. Based on experimental data obtained using RP S19 analog peptide and recombinant protein monomer, we sug...

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Detalles Bibliográficos
Autores principales: Nishiura, Hiroshi, Kawakami, Toru, Kawabe, Mutsuki, Kato-Kogoe, Nahoko, Yamada, Naoko, Nakasho, Keiji, Yamanegi, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613253/
https://www.ncbi.nlm.nih.gov/pubmed/28955891
http://dx.doi.org/10.1016/j.bbrep.2016.05.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613253/
https://www.ncbi.nlm.nih.gov/pubmed/28955891
http://dx.doi.org/10.1016/j.bbrep.2016.05.006

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