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New Evidence for the Mechanism of Action of a Type-2 Diabetes Drug Using a Magnetic Bead-Based Automated Biosensing Platform

[Image: see text] The mechanism of action (MOA) of the first line type-2 diabetes drug metformin remains unclear despite its widespread usage. However, recent evidence suggests that the mitochondrial copper (Cu)-binding action of metformin may contribute toward the drug’s MOA. Here, we present a nov...

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Detalles Bibliográficos
Autores principales: Uddin, Rokon, Nur-E-Habiba, Rena, Graham, Hwu, En-Te, Boisen, Anja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613276/
https://www.ncbi.nlm.nih.gov/pubmed/28776376
http://dx.doi.org/10.1021/acssensors.7b00384