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Probing the polarity and water environment at the protein-peptide binding interface using tryptophan analogues

7-Azatryptophan and 2,7-diazatryptophan are sensitive to polarity changes and water content, respectively, and should be ideal for studying protein-protein and protein-peptide interactions. In this study, we replaced the tryptophan in peptide Baa (LKWKKLLKLLKKLLKLG-NH(2)) with 7-azatryptophan or 2,7...

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Detalles Bibliográficos
Autores principales: Chen, Yi-Ting, Chao, Wei-Chih, Kuo, Hsiou-Ting, Shen, Jiun-Yi, Chen, I-Han, Yang, Hsiao-Ching, Wang, Jinn-Shyan, Lu, Jyh-Feng, Cheng, Richard P., Chou, Pi-Tai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613298/
https://www.ncbi.nlm.nih.gov/pubmed/28955897
http://dx.doi.org/10.1016/j.bbrep.2016.05.022