High expression of Bruton’s tyrosine kinase (BTK) is required for EGFR-induced NF-κB activation and predicts poor prognosis in human glioma

BACKGROUND: Malignant glioma is the most common primary brain tumor in adults and has a poor prognosis. However, there are no effective targeted therapies for glioma patients. Thus, the development of novel targeted therapeutics for glioma is urgently needed. METHODS: In this study, we examined the...

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Detalles Bibliográficos
Autores principales: Yue, Chenglong, Niu, Mingshan, Shan, Qian Qian, Zhou, Ting, Tu, Yiming, Xie, Peng, Hua, Lei, Yu, Rutong, Liu, Xuejiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613332/
https://www.ncbi.nlm.nih.gov/pubmed/28946903
http://dx.doi.org/10.1186/s13046-017-0600-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613332/
https://www.ncbi.nlm.nih.gov/pubmed/28946903
http://dx.doi.org/10.1186/s13046-017-0600-7

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