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High expression of Bruton’s tyrosine kinase (BTK) is required for EGFR-induced NF-κB activation and predicts poor prognosis in human glioma

BACKGROUND: Malignant glioma is the most common primary brain tumor in adults and has a poor prognosis. However, there are no effective targeted therapies for glioma patients. Thus, the development of novel targeted therapeutics for glioma is urgently needed. METHODS: In this study, we examined the...

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Detalles Bibliográficos
Autores principales:	Yue, Chenglong, Niu, Mingshan, Shan, Qian Qian, Zhou, Ting, Tu, Yiming, Xie, Peng, Hua, Lei, Yu, Rutong, Liu, Xuejiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613332/ https://www.ncbi.nlm.nih.gov/pubmed/28946903 http://dx.doi.org/10.1186/s13046-017-0600-7

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