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Creation of mouse TNFR2-selective agonistic TNF mutants using a phage display technique

Tumor necrosis factor-α (TNF), which is an immuno-modulatory cytokine, has been suggested to cause inflammatory responses as well as protection against tissue dysfunction by binding two types of TNF receptor (TNFR1/TNFR2). However, the physiological effects of TNFR2-specific activation remain unclea...

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Detalles Bibliográficos
Autores principales: Ando, Daisuke, Inoue, Masaki, Kamada, Haruhiko, Taki, Shintaro, Furuya, Takeshi, Abe, Yasuhiro, Nagano, Kazuya, Tsutsumi, Yasuo, Tsunoda, Shin-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613346/
https://www.ncbi.nlm.nih.gov/pubmed/28955920
http://dx.doi.org/10.1016/j.bbrep.2016.06.008