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Creation of mouse TNFR2-selective agonistic TNF mutants using a phage display technique
Tumor necrosis factor-α (TNF), which is an immuno-modulatory cytokine, has been suggested to cause inflammatory responses as well as protection against tissue dysfunction by binding two types of TNF receptor (TNFR1/TNFR2). However, the physiological effects of TNFR2-specific activation remain unclea...
Autores principales: | Ando, Daisuke, Inoue, Masaki, Kamada, Haruhiko, Taki, Shintaro, Furuya, Takeshi, Abe, Yasuhiro, Nagano, Kazuya, Tsutsumi, Yasuo, Tsunoda, Shin-ichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613346/ https://www.ncbi.nlm.nih.gov/pubmed/28955920 http://dx.doi.org/10.1016/j.bbrep.2016.06.008 |
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