Transforming growth factor-β-induced CUX1 isoforms are associated with fibrosis in systemic sclerosis lung fibroblasts

In the enhancer region of the human type I collagen alpha 2 (COL1A2) gene, we identified cis-elements for the transcription factor CUX1. However, the role of CUX1 in fibrosis remains unclear. Here we investigated the role of CUX1 in the regulation of COL1 expression and delineated the mechanisms und...

Descripción completa

Detalles Bibliográficos
Autores principales: Ikeda, Tetsurou, Fragiadaki, Maria, Shi-wen, Xu, Ponticos, Markella, Khan, Korsa, Denton, Christopher, Garcia, Patricia, Bou-Gharios, George, Yamakawa, Akio, Morimoto, Chikao, Abraham, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613511/
https://www.ncbi.nlm.nih.gov/pubmed/28955913
http://dx.doi.org/10.1016/j.bbrep.2016.06.022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613511/
https://www.ncbi.nlm.nih.gov/pubmed/28955913
http://dx.doi.org/10.1016/j.bbrep.2016.06.022

Ejemplares similares