Vesicle Docking Is a Key Target of Local PI(4,5)P(2) Metabolism in the Secretory Pathway of INS-1 Cells

Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)) signaling is transient and spatially confined in live cells. How this pattern of signaling regulates transmitter release and hormone secretion has not been addressed. We devised an optogenetic approach to control PI(4,5)P(2) levels in time and spac...

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Detalles Bibliográficos
Autores principales: Ji, Chen, Fan, Fan, Lou, Xuelin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613661/
https://www.ncbi.nlm.nih.gov/pubmed/28793264
http://dx.doi.org/10.1016/j.celrep.2017.07.041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613661/
https://www.ncbi.nlm.nih.gov/pubmed/28793264
http://dx.doi.org/10.1016/j.celrep.2017.07.041

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