Testosterone Upregulates the Expression of Mitochondrial ND1 and ND4 and Alleviates the Oxidative Damage to the Nigrostriatal Dopaminergic System in Orchiectomized Rats

Testosterone deficiency, as a potential risk factor for aging and aging-related neurodegenerative disorders, might induce mitochondrial dysfunction and facilitate the declines of the nigrostriatal dopaminergic system by exacerbating the mitochondrial defects and increasing the oxidative damage. Thus...

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Detalles Bibliográficos
Autores principales: Yan, Wensheng, Kang, Yunxiao, Ji, Xiaoming, Li, Shuangcheng, Li, Yingkun, Zhang, Guoliang, Cui, Huixian, Shi, Geming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613679/
https://www.ncbi.nlm.nih.gov/pubmed/29138672
http://dx.doi.org/10.1155/2017/1202459

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613679/
https://www.ncbi.nlm.nih.gov/pubmed/29138672
http://dx.doi.org/10.1155/2017/1202459

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