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Testosterone Upregulates the Expression of Mitochondrial ND1 and ND4 and Alleviates the Oxidative Damage to the Nigrostriatal Dopaminergic System in Orchiectomized Rats
Testosterone deficiency, as a potential risk factor for aging and aging-related neurodegenerative disorders, might induce mitochondrial dysfunction and facilitate the declines of the nigrostriatal dopaminergic system by exacerbating the mitochondrial defects and increasing the oxidative damage. Thus...
Autores principales: | Yan, Wensheng, Kang, Yunxiao, Ji, Xiaoming, Li, Shuangcheng, Li, Yingkun, Zhang, Guoliang, Cui, Huixian, Shi, Geming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613679/ https://www.ncbi.nlm.nih.gov/pubmed/29138672 http://dx.doi.org/10.1155/2017/1202459 |
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