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Febuxostat Modulates MAPK/NF-κBp65/TNF-α Signaling in Cardiac Ischemia-Reperfusion Injury

Xanthine oxidase and xanthine dehydrogenase have been implicated in producing myocardial damage following reperfusion of an occluded coronary artery. We investigated and compared the effect of febuxostat and allopurinol in an experimental model of ischemia-reperfusion (IR) injury with a focus on the...

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Detalles Bibliográficos
Autores principales: Khan, Sana Irfan, Malhotra, Rajiv Kumar, Rani, Neha, Sahu, Anil Kumar, Tomar, Ameesha, Garg, Shanky, Nag, Tapas Chandra, Ray, Ruma, Ojha, Shreesh, Arya, Dharamvir Singh, Bhatia, Jagriti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613710/
https://www.ncbi.nlm.nih.gov/pubmed/29138678
http://dx.doi.org/10.1155/2017/8095825