Cargando…
Febuxostat Modulates MAPK/NF-κBp65/TNF-α Signaling in Cardiac Ischemia-Reperfusion Injury
Xanthine oxidase and xanthine dehydrogenase have been implicated in producing myocardial damage following reperfusion of an occluded coronary artery. We investigated and compared the effect of febuxostat and allopurinol in an experimental model of ischemia-reperfusion (IR) injury with a focus on the...
Autores principales: | Khan, Sana Irfan, Malhotra, Rajiv Kumar, Rani, Neha, Sahu, Anil Kumar, Tomar, Ameesha, Garg, Shanky, Nag, Tapas Chandra, Ray, Ruma, Ojha, Shreesh, Arya, Dharamvir Singh, Bhatia, Jagriti |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613710/ https://www.ncbi.nlm.nih.gov/pubmed/29138678 http://dx.doi.org/10.1155/2017/8095825 |
Ejemplares similares
-
Inhibition of TGF-β by a novel PPAR-γ agonist, chrysin, salvages β-receptor stimulated myocardial injury in rats through MAPKs-dependent mechanism
por: Rani, Neha, et al.
Publicado: (2015) -
Therapeutic Potential and Molecular Mechanisms of Emblica officinalis Gaertn in Countering Nephrotoxicity in Rats Induced by the Chemotherapeutic Agent Cisplatin
por: Malik, Salma, et al.
Publicado: (2016) -
Seabuckthorn Pulp Oil Protects against Myocardial Ischemia–Reperfusion Injury in Rats through Activation of Akt/eNOS
por: Suchal, Kapil, et al.
Publicado: (2016) -
Corrigendum: Seabuckthorn Pulp Oil Protects against Myocardial Ischemia–Reperfusion Injury in Rats through Activation of Akt/eNOS
por: Suchal, Kapil, et al.
Publicado: (2019) -
Molecular Pathways Involved in the Amelioration of Myocardial Injury in Diabetic Rats by Kaempferol
por: Suchal, Kapil, et al.
Publicado: (2017)