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Soluble Epoxide Hydrolase Inhibitor and 14,15-Epoxyeicosatrienoic Acid-Facilitated Long-Term Potentiation through cAMP and CaMKII in the Hippocampus

Epoxyeicosatrienoic acids (EETs) are derived from arachidonic acid and metabolized by soluble epoxide hydrolase (sEH). The role of EETs in synaptic function in the central nervous system is still largely unknown. We found that pharmacological inhibition of sEH to stabilize endogenous EETs and exogen...

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Detalles Bibliográficos
Autores principales: Wu, Han-Fang, Chen, Yi-Ju, Wu, Su-Zhen, Lee, Chi-Wei, Chen, I-Tuan, Lee, Yi-Chao, Huang, Chi-Chen, Hsing, Chung-Hsi, Tang, Chih-Wei, Lin, Hui-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613711/
https://www.ncbi.nlm.nih.gov/pubmed/29138698
http://dx.doi.org/10.1155/2017/3467805