Genetic background modifies amyloidosis in a mouse model of ATTR neuropathy

Penetrance and age of onset of ATTRV30M amyloidotic neuropathy varies significantly among different populations. This variability has been attributed to both genetic and environmental modifiers. We studied the effect of genetic background on phenotype in two lines of transgenic mice bearing the same...

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Detalles Bibliográficos
Autores principales: Panayiotou, E., Papacharalambous, R., Antoniou, A., Christophides, G., Papageorgiou, L., Fella, E., Malas, S., Kyriakides, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613746/
https://www.ncbi.nlm.nih.gov/pubmed/28955941
http://dx.doi.org/10.1016/j.bbrep.2016.08.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613746/
https://www.ncbi.nlm.nih.gov/pubmed/28955941
http://dx.doi.org/10.1016/j.bbrep.2016.08.005

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