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Genetic background modifies amyloidosis in a mouse model of ATTR neuropathy
Penetrance and age of onset of ATTRV30M amyloidotic neuropathy varies significantly among different populations. This variability has been attributed to both genetic and environmental modifiers. We studied the effect of genetic background on phenotype in two lines of transgenic mice bearing the same...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613746/ https://www.ncbi.nlm.nih.gov/pubmed/28955941 http://dx.doi.org/10.1016/j.bbrep.2016.08.005 |