Oncogene-Expressing Senescent Melanocytes Up-Regulate MHC Class II, a Candidate Melanoma Suppressor Function

On acquisition of an oncogenic mutation, primary human and mouse cells can enter oncogene-induced senescence (OIS). OIS is characterized by a stable proliferation arrest and secretion of proinflammatory cytokines and chemokines, the senescence-associated secretory phenotype. Proliferation arrest and...

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Detalles Bibliográficos
Autores principales: van Tuyn, John, Jaber-Hijazi, Farah, MacKenzie, Douglas, Cole, John J., Mann, Elizabeth, Pawlikowski, Jeff S., Rai, Taranjit Singh, Nelson, David M., McBryan, Tony, Ivanov, Andre, Blyth, Karen, Wu, Hong, Milling, Simon, Adams, Peter D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613751/
https://www.ncbi.nlm.nih.gov/pubmed/28647344
http://dx.doi.org/10.1016/j.jid.2017.05.030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613751/
https://www.ncbi.nlm.nih.gov/pubmed/28647344
http://dx.doi.org/10.1016/j.jid.2017.05.030

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