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Proteolytic processing and inactivation of CCL2/MCP-1 by meprins

Monocyte chemotactic protein 1 (CCL2/MCP-1) is a small chemokine involved in the recruitment and trafficking of mononuclear immune cells to inflammation sites. Our studies demonstrate that the metalloendopeptidases meprin A (purified from kidney cortex), recombinant meprin α, and recombinant meprin...

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Detalles Bibliográficos
Autores principales: Herzog, Christian, Haun, Randy S., Shah, Sudhir V., Kaushal, Gur P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613766/
https://www.ncbi.nlm.nih.gov/pubmed/28955950
http://dx.doi.org/10.1016/j.bbrep.2016.08.019