Cargando…

Proteolytic processing and inactivation of CCL2/MCP-1 by meprins

Monocyte chemotactic protein 1 (CCL2/MCP-1) is a small chemokine involved in the recruitment and trafficking of mononuclear immune cells to inflammation sites. Our studies demonstrate that the metalloendopeptidases meprin A (purified from kidney cortex), recombinant meprin α, and recombinant meprin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Herzog, Christian, Haun, Randy S., Shah, Sudhir V., Kaushal, Gur P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613766/ https://www.ncbi.nlm.nih.gov/pubmed/28955950 http://dx.doi.org/10.1016/j.bbrep.2016.08.019

Ejemplares similares

Hypoxia Associated Proteolytic Processing of OS-9 by the Metalloproteinase Meprin β
por: Martin, Barry Lee, et al.
Publicado: (2016)

The substrate degradome of meprin metalloproteases reveals an unexpected proteolytic link between meprin β and ADAM10
por: Jefferson, Tamara, et al.
Publicado: (2012)

Proteolytic processing of galectin-3 by meprin metalloproteases is crucial for host-microbiome homeostasis
por: Bülck, Cynthia, et al.
Publicado: (2023)

Distinct contributions of meprins to skin regeneration after injury – Meprin α a physiological processer of pro-collagen VII
por: Kruppa, Daniel, et al.
Publicado: (2021)

The metalloproteases meprin α and meprin β: unique enzymes in inflammation, neurodegeneration, cancer and fibrosis
por: Broder, Claudia, et al.
Publicado: (2013)

CCL2/MCP-1 modulation of microglial activation and proliferation
por: Hinojosa, Ara E, et al.
Publicado: (2011)

Origin and Diversification of Meprin Proteases
por: Marín, Ignacio
Publicado: (2015)

Heteroaromatic Inhibitors of the Astacin Proteinases Meprin α, Meprin β and Ovastacin Discovered by a Scaffold‐Hopping Approach
por: Tan, Kathrin, et al.
Publicado: (2020)

The Metalloprotease Meprinβ Processes E-Cadherin and Weakens Intercellular Adhesion
por: Huguenin, Maya, et al.
Publicado: (2008)

Hypoxia-inducible factor-1 (HIF-1) is involved in the regulation of hypoxia-stimulated expression of monocyte chemoattractant protein-1 (MCP-1/CCL2) and MCP-5 (Ccl12) in astrocytes
por: Mojsilovic-Petrovic, Jelena, et al.
Publicado: (2007)

Meprin β contributes to collagen deposition in lung fibrosis
por: Biasin, V., et al.
Publicado: (2017)

Differences in Shedding of the Interleukin-11 Receptor by the Proteases ADAM9, ADAM10, ADAM17, Meprin α, Meprin β and MT1-MMP
por: Sammel, Martin, et al.
Publicado: (2019)

The Metalloprotease Meprin β Is an Alternative β-Secretase of APP
por: Becker-Pauly, Christoph, et al.
Publicado: (2017)

New links for meprin β within the protease web
por: Canbay, Vahap, et al.
Publicado: (2022)

The putative pleiotropic functions of meprin β in gastric cancer
por: Siemsen, Wiebke, et al.
Publicado: (2023)

Detection of human MCP-4/CCL13 isoforms by SELDI immunoaffinity capture
por: Rossi, Leonardo, et al.
Publicado: (2006)

CCL2/MCP-I Genotype-Phenotype Relationship in Latent Tuberculosis Infection
por: Hussain, Rabia, et al.
Publicado: (2011)

CCL2/MCP-1 signaling drives extracellular matrix turnover by diverse macrophage subsets()
por: Jürgensen, Henrik J., et al.
Publicado: (2019)

Discovery and Optimization of Selective Inhibitors of Meprin α (Part I)
por: Hou, Shurong, et al.
Publicado: (2021)

Discovery and Optimization of Selective Inhibitors of Meprin α (Part II)
por: Wang, Chao, et al.
Publicado: (2021)

Mammalian Glycosylation Patterns Protect Citrullinated Chemokine MCP-1/CCL2 from Partial Degradation
por: Korchynskyi, Olexandr, et al.
Publicado: (2023)

Structure and Dynamics of Meprin β in Complex with a Hydroxamate-Based Inhibitor
por: Linnert, Miriam, et al.
Publicado: (2021)

Synthesis and structure–activity relationships of pyrazole-based inhibitors of meprin α and β
por: Tan, Kathrin, et al.
Publicado: (2023)

Monocyte Chemoattractant Protein-1 (MCP-1/CCL2) Drives Activation of Bone Remodelling and Skeletal Metastasis
por: Mulholland, Bridie S., et al.
Publicado: (2019)

Phosphorylation of the amyloid precursor protein (APP) at Ser-675 promotes APP processing involving meprin β
por: Menon, Preeti Kumaran, et al.
Publicado: (2019)

Helical ultrastructure of the metalloprotease meprin α in complex with a small molecule inhibitor
por: Bayly-Jones, Charles, et al.
Publicado: (2022)

Serum levels of NLRC4 and MCP-2/CCL8 in patients with active Crohn’s disease
por: Irak, Kader, et al.
Publicado: (2021)

Pro-Inflammatory Chemokine CCL2 (MCP-1) Promotes Healing in Diabetic Wounds by Restoring the Macrophage Response
por: Wood, Stephen, et al.
Publicado: (2014)

Central Role for MCP-1/CCL2 in Injury-Induced Inflammation Revealed by In Vitro, In Silico, and Clinical Studies
por: Ziraldo, Cordelia, et al.
Publicado: (2013)

-2518A/G polymorphism of monocyte chemotactic protein 1 (MCP-1/CCL2) is associated with cutaneous mastocytosis
por: Ługowska-Umer, Hanna, et al.
Publicado: (2022)

Macrophage-Derived Factors with the Potential to Contribute to Pathogenicity of HIV-1 and HIV-2: Role of CCL-2/MCP-1
por: Gao, Chunling, et al.
Publicado: (2023)

Neprilysin Inhibits Coagulation through Proteolytic Inactivation of Fibrinogen
por: Burrell, Matthew, et al.
Publicado: (2016)

Association of Early Nasopharyngeal Immune Markers With COVID-19 Clinical Outcome: Predictive Value of CCL2/MCP-1
por: Sierra, Beatriz, et al.
Publicado: (2020)

Metalloproteases and Proteolytic Processing
por: Turner, Anthony J., et al.
Publicado: (2010)

Metalloprotease Meprinβ in Rat Kidney: Glomerular Localization and Differential Expression in Glomerulonephritis
por: Oneda, Beatrice, et al.
Publicado: (2008)

Proceedings: Radioprotective effectivity of alphamercaptopropionylglycine (Thiola, Meprin) and study of its SH activity.
por: Sántha, A., et al.
Publicado: (1975)

Mammalian plasma fetuin-B is a selective inhibitor of ovastacin and meprin metalloproteinases
por: Karmilin, Konstantin, et al.
Publicado: (2019)

A preliminary study of possible fibrotic role of meprin metalloproteases in scleroderma patients
por: Koçak, Ayşe, et al.
Publicado: (2021)

Evolution and Expression of the Meprin and TRAF Homology Domain-Containing Gene Family in Solanaceae
por: Dai, Yangshuo, et al.
Publicado: (2023)

Cell Surface Processing of CD109 by Meprin β Leads to the Release of Soluble Fragments and Reduced Expression on Extracellular Vesicles
por: Lückstädt, Wiebke, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_elvea93080lo1q3jhnvmak6vg4