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The low molecular weight fraction of human serum albumin upregulates COX2, prostaglandin E2, and prostaglandin D2 under inflammatory conditions in osteoarthritic knee synovial fibroblasts

BACKGROUND: The ability to decrease inflammation and promote healing is important in the intervention and management of a variety of disease states, including osteoarthritis of the knee (OAK). Even though cyclooxygenase 2 (COX2) has an established pro-inflammatory role, evidence suggests it is also...

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Detalles Bibliográficos
Autores principales: Frederick, Elizabeth D., Hausburg, Melissa A., Thomas, Gregory W., Rael, Leonard T., Brody, Edward, Bar-Or, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613771/
https://www.ncbi.nlm.nih.gov/pubmed/28955943
http://dx.doi.org/10.1016/j.bbrep.2016.08.015