Hypoxia-Activated Alkylating Agents in BRCA1-Mutant Ovarian Serous Carcinoma

Breast cancer 1 antigen (BRCA 1) and breast cancer 2 antigen (BRCA2) genes play a significant role in deoxyribonucleic acid (DNA) repair by means of interstrand crosslink repair, and deleterious germline mutations of these are responsible for most hereditary breast and ovarian cancers. Therapeutic s...

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Detalles Bibliográficos
Autores principales: Conroy, Michael, Borad, Mitesh J, Bryce, Alan H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2017
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613928/
https://www.ncbi.nlm.nih.gov/pubmed/28959512
http://dx.doi.org/10.7759/cureus.1517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613928/
https://www.ncbi.nlm.nih.gov/pubmed/28959512
http://dx.doi.org/10.7759/cureus.1517

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