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Anti-IL-17A blocking antibody reduces cyclosporin A-induced relapse in experimental autoimmune encephalomyelitis mice

Cyclosporin A (CsA) is effective at reducing pathogenic immune responses, but upon withdrawal of CsA the immune response often “rebounds” resulting in a relapse or exacerbation of disease. The mechanisms, cells and cytokines involved in the relapse or exacerbation after CsA withdrawal are unknown. W...

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Detalles Bibliográficos
Autores principales: Saitoh, Kodai, Kon, Shigeyuki, Nakatsuru, Takuya, Inui, Kyosuke, Ihara, Takeru, Matsumoto, Naoki, Kitai, Yuichi, Muromoto, Ryuta, Matsuda, Tadashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613930/
https://www.ncbi.nlm.nih.gov/pubmed/28955949
http://dx.doi.org/10.1016/j.bbrep.2016.08.021