Cargando…

Recombinant α- β- and γ-Synucleins Stimulate Protein Phosphatase 2A Catalytic Subunit Activity in Cell Free Assays

α-Synuclein (aSyn), β-Synuclein (bSyn), and γ-Synuclein (gSyn) are members of a conserved family of chaperone-like proteins that are highly expressed in vertebrate neuronal tissues. Of the three synucleins, only aSyn has been strongly implicated in neurodegenerative disorders such as Parkinson'...

Descripción completa

Detalles Bibliográficos
Autores principales: Lek, Sovanarak, Vargas-Medrano, Javier, Villanueva, Ernesto, Marcus, Brian, Godfrey, Wesley, Perez, Ruth G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614314/
https://www.ncbi.nlm.nih.gov/pubmed/28829427
http://dx.doi.org/10.3791/55361