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Recombinant α- β- and γ-Synucleins Stimulate Protein Phosphatase 2A Catalytic Subunit Activity in Cell Free Assays
α-Synuclein (aSyn), β-Synuclein (bSyn), and γ-Synuclein (gSyn) are members of a conserved family of chaperone-like proteins that are highly expressed in vertebrate neuronal tissues. Of the three synucleins, only aSyn has been strongly implicated in neurodegenerative disorders such as Parkinson'...
Autores principales: | Lek, Sovanarak, Vargas-Medrano, Javier, Villanueva, Ernesto, Marcus, Brian, Godfrey, Wesley, Perez, Ruth G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MyJove Corporation
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614314/ https://www.ncbi.nlm.nih.gov/pubmed/28829427 http://dx.doi.org/10.3791/55361 |
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