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Synergy of Dendritic Cell Vaccines and Avasimibe in Treatment of Head and Neck Cancer in Mice

BACKGROUND: The main purpose of this study was to explore the antitumor effect and mechanisms of ACAT1 inhibitor combined with CSCs-DC vaccine. MATERIAL/METHODS: We isolated HNSCC CSCs and gained CSCs antigens, then used CSCs antigens to load dendritic cells (DC) and generated a CSCs-DC vaccine. We...

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Detalles Bibliográficos
Autores principales: Chen, Xin, Song, Qibin, Xia, Leiming, Xu, Ximing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614335/
https://www.ncbi.nlm.nih.gov/pubmed/28918429
http://dx.doi.org/10.12659/MSM.905814