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The C-terminal domain of glyceraldehyde 3-phosphate dehydrogenase plays an important role in suppression of tRNA(Lys3) packaging into human immunodeficiency virus type-1 particles
Human immunodeficiency virus type-1 (HIV-1) requires the packaging of human tRNA(Lys3) as a primer for effective viral reverse transcription. Previously, we reported that glyceraldehyde 3-phosphate dehydrogenase (GAPDH) suppresses the packaging efficiency of tRNA(Lys3). Although the binding of GAPDH...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614461/ https://www.ncbi.nlm.nih.gov/pubmed/28955972 http://dx.doi.org/10.1016/j.bbrep.2016.09.015 |