The C-terminal domain of glyceraldehyde 3-phosphate dehydrogenase plays an important role in suppression of tRNA(Lys3) packaging into human immunodeficiency virus type-1 particles

Human immunodeficiency virus type-1 (HIV-1) requires the packaging of human tRNA(Lys3) as a primer for effective viral reverse transcription. Previously, we reported that glyceraldehyde 3-phosphate dehydrogenase (GAPDH) suppresses the packaging efficiency of tRNA(Lys3). Although the binding of GAPDH...

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Detalles Bibliográficos
Autores principales: Kishimoto, Naoki, Onitsuka-Kishimoto, Ayano, Iga, Nozomi, Takamune, Nobutoki, Shoji, Shozo, Misumi, Shogo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614461/
https://www.ncbi.nlm.nih.gov/pubmed/28955972
http://dx.doi.org/10.1016/j.bbrep.2016.09.015

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