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A 3D-psoriatic skin model for dermatological testing: The impact of culture conditions

BACKGROUND: Inadequate representation of the human tissue environment during a preclinical screen can result in inaccurate predictions of compound effects. Consequently, pharmaceutical investigators are searching for preclinical models that closely resemble original tissue for predicting clinical ou...

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Detalles Bibliográficos
Autores principales: Duque-Fernandez, Alexandra, Gauthier, Lydia, Simard, Mélissa, Jean, Jessica, Gendreau, Isabelle, Morin, Alexandre, Soucy, Jacques, Auger, Michèle, Pouliot, Roxane.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614463/
https://www.ncbi.nlm.nih.gov/pubmed/28955966
http://dx.doi.org/10.1016/j.bbrep.2016.09.012