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A 3D-psoriatic skin model for dermatological testing: The impact of culture conditions
BACKGROUND: Inadequate representation of the human tissue environment during a preclinical screen can result in inaccurate predictions of compound effects. Consequently, pharmaceutical investigators are searching for preclinical models that closely resemble original tissue for predicting clinical ou...
Autores principales: | Duque-Fernandez, Alexandra, Gauthier, Lydia, Simard, Mélissa, Jean, Jessica, Gendreau, Isabelle, Morin, Alexandre, Soucy, Jacques, Auger, Michèle, Pouliot, Roxane. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614463/ https://www.ncbi.nlm.nih.gov/pubmed/28955966 http://dx.doi.org/10.1016/j.bbrep.2016.09.012 |
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