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Vibrio cholerae hemolysin: The β-trefoil domain is required for folding to the native conformation

Vibrio cholerae cytolysin/hemolysin (VCC) is a 65 kDa β-pore-forming toxin causing lysis and death of eukaryotic cells. Apart from the core cytolysin domain, VCC has two lectin domains with β-trefoil and β-prism folds. The β-prism domain binds to cell surface carbohydrate receptors; the role of the...

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Detalles Bibliográficos
Autores principales: Mukherjee, Amarshi, Ganguly, Sreerupa, Chatterjee, Nabendu S., Banerjee, Kalyan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614477/
https://www.ncbi.nlm.nih.gov/pubmed/28955962
http://dx.doi.org/10.1016/j.bbrep.2016.09.009