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Crk II silencing down-regulates IGF-IR and inhibits migration and invasion of prostate cancer cells
Crk (C10 regulator of kinase) adaptor proteins are highly expressed in many types of human cancers and often contribute to aggressive cancer phenotypes. Crk II, a member of CRK family, has been reported to regulate cell migration and metastasis in breast cancer cells. However, its role in other canc...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614478/ https://www.ncbi.nlm.nih.gov/pubmed/28955980 http://dx.doi.org/10.1016/j.bbrep.2016.10.009 |