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Crk II silencing down-regulates IGF-IR and inhibits migration and invasion of prostate cancer cells

Crk (C10 regulator of kinase) adaptor proteins are highly expressed in many types of human cancers and often contribute to aggressive cancer phenotypes. Crk II, a member of CRK family, has been reported to regulate cell migration and metastasis in breast cancer cells. However, its role in other canc...

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Detalles Bibliográficos
Autores principales: Dhupkar, Pooja, Zhao, Huang, Mujoo, Kalpana, An, Zhiqiang, Zhang, Ningyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614478/
https://www.ncbi.nlm.nih.gov/pubmed/28955980
http://dx.doi.org/10.1016/j.bbrep.2016.10.009