nsPEF-induced PIP(2) depletion, PLC activity and actin cytoskeletal cortex remodeling are responsible for post-exposure cellular swelling and blebbing

Cell swelling and blebbing has been commonly observed following nanosecond pulsed electric field (nsPEF) exposure. The hypothesized origin of these effects is nanoporation of the plasma membrane (PM) followed by transmembrane diffusion of extracellular fluid and disassembly of cortical actin structu...

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Detalles Bibliográficos
Autores principales: Tolstykh, Gleb P., Thompson, Gary L., Beier, Hope T., Steelman, Zachary A., Ibey, Bennett L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614542/
https://www.ncbi.nlm.nih.gov/pubmed/28955986
http://dx.doi.org/10.1016/j.bbrep.2016.11.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614542/
https://www.ncbi.nlm.nih.gov/pubmed/28955986
http://dx.doi.org/10.1016/j.bbrep.2016.11.005

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